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Leptin resistance

Leptin Resistance is a physiological condition in which our body cells fail to response and re-act to the normal action of the leptin hormone.

Recent researches often give information regarding the diet and the effects, both positive and negative about the foods taken. The common knowledge is that when the calories taken are more than necessary, it is stored fat and obesity is the result. When the body fails to recognize any food as energy, then it has to be understood that food cannot be assimilated. Absorption of food is required to convert the food into energy and remaining healthy and fit. Various hormones have a dynamic role to play when it comes to assimilation of food. Leptin is one of the important hormones, in fact the chieftain in the process of absorption of food.

Leptin resistance has no single definition, but is a connotation of the distinct meanings which are used by the investigators in different scenarios. It can be described as the failure of leptin to endorse expected useful metabolic outcomes in case of over nutrition.

Functions of Leptin hormone

Leptin has various functions and what makes it critical to food assimilation is that it is the hormone that communicates to the hypothalamus of the brain about the fat levels in the body, and informs if it is required to eat, or if the calorie can be burnt at the normal rate. Leptin also play a vital role in immunity, brain function and in fertility. Regulation of energy balance is where Leptin is required. Survival is based on eating, but overeating or starvation can both cause starvation to stop. Leptin tells if it is required to eat or not to eat. The fat cells are the production center of the Leptin hormones. When fat is more, Leptin is carried more. When the Leptin levels in the blood drops, brain understands the need to eat, and when eating the levels rise and the brain gets the signal to stop eating.

Leptin Receptors and Resistance:

With too many calories are consumed the receptors of the Leptin in the brain are worn out.  This can lead to Leptin resistance. 5 to 6 meals per day are recommended by the fitness trainers and the dieticians these days to lose weight. For a few people, still losing weight can be a tedious task. This is because when an individual eats food the Leptin level rises. This means that anything that is eaten like fruits, protein shakes, and all such foods except for water, increase the level of Leptin in the blood. When the Leptin levels keep rising every time one eats, the result is Leptin resistance. This means that the receptors fail to notice the levels of increased Leptin in blood. As a result, there is not satiation achieved, and the individual feels hungry as the brain think the body starves. As a result one takes in lots of calories than the calories burned. This also leads to slowing down of metabolism, which means energy is conserved for the supposed famine. This is the same process that happens when one eats very less. The body starts to store fats for the emergency. The best way to lose weight when there is Leptin resistance is to eat 3 times a day with a minimum of 5 hours gap in between each meal. Munching any snack and drinking everything that comes near can lead to the wear and tear of the receptors in the brain and higher chances of Leptin resistance do exist.